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Johnson & Johnson and DePuy Orthopaedics announced a recall of the DePuy ASR hip replacement due to a high failure rate. Learn about the dangerous side effects of Accutane, including Ulcerative Colitis and Crohn's Disease. Our asbestos lawyers can help if you or a loved one has been diagnosed with mesothelioma due to asbestos exposure. Read about how our landmark U.S. Supreme Court victory benefited consumers across America. The FDA now requires the manufacturer of Levaquin to include a black box warning to alert patients to the risk of tendon ruptures.

Prempro Lawsuit

 

Jury Finds Prempro Caused Breast Cancer, Awards Three Women $134.5 Million

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October 11, 2007—A Nevada jury awarded $134.5 million to three women who developed breast cancer following use of Prempro and Premarin. The verdict was the largest against drugmaker Wyeth related to its hormone replacement therapy.

A fourth woman settled before trial and passed away in April 2007 at the age of 59.

 

Jury Awards $3 Million in Prempro Case

  February 20, 2007—A jury in Philadelphia found that Prempro caused Jennie Nelson's breast cancer and awarded her and her husband $3 million in damages. Nelson previously had been awarded $1.5 million by a jury in October 2006, but a mistrial was declared after the verdict had been returned.
 

Wyeth Loses Prempro Trial, Ordered to Pay $1.5 Million in Damages

prempro hrt study January 29, 2007—A Philadelphia jury found that Prempro was responsible for Mary Daniel's breast cancer and ordered Wyeth to pay $1.5 million in compensatory damages. The jury concluded that Wyeth was negligent in failing to provide adequate warnings about the risk of breast cancer associated with Prempro.
 

Study Links Prempro to Breast Cancer, Other Serious Side Effects

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May 31, 2002—The National Heart, Lung and Blood Institute (NHLBI) abruptly halted a clinical trial assessing the long term effects of Prempro after determining the side effects were so severe that they could not continue to give Prempro to the participants.

The NHLBI study, conducted under the guidance of the federal government, consisted of more than 16,000 women between the ages of 50 and 79. The Data and Safety Monitoring Board made the decision to terminate the clinical trial based on concerns of increased risk of breast cancer and heart problems.

According to the NHLBI, women who were given Prempro were more likely to develop serious problems compared to those in the placebo group.

  • 26% increase in breast cancer
  • 41% increase in strokes
  • 100% increase in blood clots
  • 22% increase in incidents of cardiovascular disease.

Additional Prempro side effects include ovarian cancer, lupus and gall bladder cancer. A study released in May 2003 by the American Medical Association also noted increased risk of Alzheimer's disease and other forms of dementia.

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Prempro News

Pfizer Settles Prempro Case on Breast Cancer Before Retrial on Damages • Blomberg • August 27, 2010

Study Makes Stronger Case HRT Causes Breast Cancer • Reuters • February 4, 2009

Elsevier Looks Into Charge of Ghostwriting by Wyeth • Wall Street Journal • December 22, 2008

Elsevier to Review Senator's Claim • The New York Times • December 19, 2008

Wyeth's Use of Medical Ghostwriters Questioned • The New York Times • December 12, 2008

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